Typical Appearance and Warning Signs of Melanoma
Melanoma can appear in many forms, which is why recognizing early warning signs is so important. It often begins as a new spot on the skin or a change in an existing mole. One common way to remember what to look for is by using the ABCDEs of Melanoma:
- A – Asymmetry: One half of the mole doesn’t mirror the other half in shape, size, or color.
- B – Border: The edges are irregular, ragged, or blurred instead of smooth and sharp.
- C – Color: The mole shows multiple shades—such as brown, black, red, white, or blue—or changes color over time.
- D – Diameter: The spot is larger than 6 millimeters (about the size of a pencil eraser), though melanomas can be smaller.
- E – Evolving: The mole is changing in size, color, shape, or symptoms—such as itching, bleeding, or crusting. This is the most important sign. Even if the lesion you are looking at does not meet the A, B, C, or D criteria, a changing mole is concerning and should be evaluated.
Melanoma lesions may also stand out as the “ugly duckling”—a mole that looks different from your others—or appear in unexpected places such as under nails, on the palms or soles, or on mucous membranes. Because melanoma can spread rapidly, early detection is critical. If you notice any spot that looks unusual or is changing, schedule an evaluation right away.


